The Philippine Biology Olympiad (PBO) is the country's premier biology competition for students in grades 7 to 12. It serves as the venue for selection of the country's four student delegates to the annual International Biology Olympiad (IBO). The Department of Science and Technology - Science Education Institute (DOST-SEI) has endorsed the Department of Biology of the Ateneo de Manila University and the Ateneo Biological Organization - eXplore. eXperience. eXcel. (BOx) as the official organizers of the PBO. It consists mainly of the Quiz Bee and the Laboratory Skills Test.

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For the year 2021, all phases and activities of the competition will be facilitated through online platforms to ensure the safety of participants and organizers. All activities arising from the competition aim to enhance the students' interest, passion, and skills in the biological sciences; increase awareness on issues in biology, particularly biodiversity; and promote camaraderie among young biologists in the making.